Jon Cryer is expected to make a big return to primetime comedy.
The two-time Emmy winner has landed the starring role in the forthcoming MCTV 700 ABC pilot Losing It, according to The Hollywood Reporter.
It has been two years since the actor returned to a full-time broadcast TV gig after wrapping a 12-year run on the CBS hit Two And A Half Men.
In Losing It, he will star as Andy, an acupuncturist who finds relief in the Eastern medicine practice as he tussles with his nutty family members, who are losing their minds.
Andy has become the caretaker of his father, with whom he has never been close, while he faces marital woes after finding out that his wife has been having an affair.
The premise revolves around three siblings who are dealing with their parents, as well as challenges such as divorce, parenthood and early-onset dementia.
The half-hour comedy will co-star Parks And Recreation alum Natalie Morales as Andy's sister.
Jon enjoyed great success on Two And A Half Men, earning seven Primetime Emmy Award nominations and two wins as Alan, the uptight brother who moves with his son to live with his brother Charlie, played by Charlie Sheen.
However, Sheen left amid addiction treatment and a dispute with the series producer Chuck Lorre.
Ashton Kutcher stepped in to star opposite Jon in the final four seasons after Charlie was killed off on the comedy.
Since leaving Two And A Half Men, the Pretty In Pink actor has had guest spots on his former producer's shows Mom and NCIS.